Аннотация: Water resources in areas with unfavorable climatic characteristics are indicators of the well-being of the local population. In particular, in the healthcare system. The flora and fauna that a person feeds also depends on the quality of the water, its mineralization. Respiratory diseases, asthma, stone diseases, etc. are developed in the republic. In the last codes, urolithiasis in young people began to be registered. The desertification process in the region occupies the main platform in the ecological balance of the system. The formed desert zone in the eastern and southern regions of Kalmykia is expanding every year. This leads to the appearance of dust storms, dry winds, which has a negative effect on the ecological and economic potential of the republic. The complex climatic characteristics of the region, in particular the lack of water resources, their salinization, mineralization, negatively affect agriculture and land reclamation. And the data of 2020, when the whole republic was covered with a dust storm that lasted more than a week, led to difficult economic consequences. The drought led to a sharp decline in livestock numbers and mortality. The results obtained will make it possible to comprehensively assess the economic situation in the region associated with the exploitation of the soil and upper lithospheric layer. The relevance of these studies is in identifying the main natural and anthropogenic factors affecting mainly the ecology and economy in the region. The obtained results of the study will make it possible to develop a number of measures to strengthen the sands and move them. The object of the study is the regions in which desert territories were formed, for example, Chernye Zemli, which was attributed to several regions of Kalmykia. The subject of the research is the consideration of the influence of the desertification process, wind load, climatic parameters. The hypothesis is that a communication system was adopted in the chain of geological-geographical object and natural environment. Entropy of its equilibrium state.