Аннотация: Since the first application of anti-Russian sanctions, Russia's role as one of the most important participants in international integration has significantly decreased. This has led to global changes in the entire structure of relations between the participating countries. At the present time, the world is experiencing a global economic crisis, which is a negative factor on the way to the establishment of stable trade and market relations. The article examines the main factors of the impact of sanctions on the political and economic situation in the world as a whole.